<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2023 Workiva-->
<!--r:304e05d8-1df4-4086-a0f9-a15271ab8170,g:6db1f415-818c-469e-ba5a-cacdad940712-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/UnauditedCondensedConsolidatedStatementsofFinancialCondition" xlink:type="simple" xlink:href="gbci-20230331.xsd#UnauditedCondensedConsolidatedStatementsofFinancialCondition"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/UnauditedCondensedConsolidatedStatementsofFinancialCondition" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAfterAllowanceForCreditLoss_b552e204-ae1f-4cb4-9e69-82f6a125b070" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestAfterAllowanceForCreditLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_2150af7c-a392-4e35-9c2b-a939290264b4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAfterAllowanceForCreditLoss_b552e204-ae1f-4cb4-9e69-82f6a125b070" xlink:to="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_2150af7c-a392-4e35-9c2b-a939290264b4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest_d27d18a3-097f-4cd0-8ecb-805ad4d97677" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAfterAllowanceForCreditLoss_b552e204-ae1f-4cb4-9e69-82f6a125b070" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossExcludingAccruedInterest_d27d18a3-097f-4cd0-8ecb-805ad4d97677" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_6f03834c-2814-4c28-a5df-66ed74ef03f3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_107af01f-d7a1-427b-a286-ea95963d49c1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Liabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_6f03834c-2814-4c28-a5df-66ed74ef03f3" xlink:to="loc_us-gaap_Liabilities_107af01f-d7a1-427b-a286-ea95963d49c1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_d334c8d8-ff2c-420d-b8fb-796fe1e6540f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_6f03834c-2814-4c28-a5df-66ed74ef03f3" xlink:to="loc_us-gaap_CommitmentsAndContingencies_d334c8d8-ff2c-420d-b8fb-796fe1e6540f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_ee3b66e8-ec1a-417f-ae0d-eb8ba4f3dec7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_6f03834c-2814-4c28-a5df-66ed74ef03f3" xlink:to="loc_us-gaap_StockholdersEquity_ee3b66e8-ec1a-417f-ae0d-eb8ba4f3dec7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsAndFederalFundsSold_06be34e5-414a-4ad3-86b4-30dc0dcf20b6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsAndFederalFundsSold"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndDueFromBanks_1bd7960d-7581-4a4b-87e5-9af092568664" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndDueFromBanks"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsAndFederalFundsSold_06be34e5-414a-4ad3-86b4-30dc0dcf20b6" xlink:to="loc_us-gaap_CashAndDueFromBanks_1bd7960d-7581-4a4b-87e5-9af092568664" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDepositsInBanks_bbe8f754-9caf-488e-acf4-a4cfae514f31" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestBearingDepositsInBanks"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsAndFederalFundsSold_06be34e5-414a-4ad3-86b4-30dc0dcf20b6" xlink:to="loc_us-gaap_InterestBearingDepositsInBanks_bbe8f754-9caf-488e-acf4-a4cfae514f31" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_e41de743-852f-4f8f-9bce-a7131c6ee7d7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestBearingDepositLiabilities_bd43f129-b548-4864-a295-3363b77e4eeb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestBearingDepositLiabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e41de743-852f-4f8f-9bce-a7131c6ee7d7" xlink:to="loc_us-gaap_NoninterestBearingDepositLiabilities_bd43f129-b548-4864-a295-3363b77e4eeb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestBearingDepositLiabilities_efd18504-6b46-4ab2-9509-9590f18991b2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestBearingDepositLiabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e41de743-852f-4f8f-9bce-a7131c6ee7d7" xlink:to="loc_us-gaap_InterestBearingDepositLiabilities_efd18504-6b46-4ab2-9509-9590f18991b2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuritiesSoldUnderAgreementsToRepurchase_7adc6c31-6cc5-421e-bb7b-684cbb1c29d7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SecuritiesSoldUnderAgreementsToRepurchase"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e41de743-852f-4f8f-9bce-a7131c6ee7d7" xlink:to="loc_us-gaap_SecuritiesSoldUnderAgreementsToRepurchase_7adc6c31-6cc5-421e-bb7b-684cbb1c29d7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherBorrowings_364919df-3ba5-438d-8150-04463740ef7a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherBorrowings"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e41de743-852f-4f8f-9bce-a7131c6ee7d7" xlink:to="loc_us-gaap_OtherBorrowings_364919df-3ba5-438d-8150-04463740ef7a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubordinatedDebt_0415b855-0c9f-4b96-a40e-c916faf9124d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubordinatedDebt"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e41de743-852f-4f8f-9bce-a7131c6ee7d7" xlink:to="loc_us-gaap_SubordinatedDebt_0415b855-0c9f-4b96-a40e-c916faf9124d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestPayableCurrentAndNoncurrent_95bd6c23-1fa2-4177-8129-597277e1e015" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestPayableCurrentAndNoncurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e41de743-852f-4f8f-9bce-a7131c6ee7d7" xlink:to="loc_us-gaap_InterestPayableCurrentAndNoncurrent_95bd6c23-1fa2-4177-8129-597277e1e015" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilities_9f946f80-3b47-420a-9e54-a766bf550d46" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherLiabilities"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e41de743-852f-4f8f-9bce-a7131c6ee7d7" xlink:to="loc_us-gaap_OtherLiabilities_9f946f80-3b47-420a-9e54-a766bf550d46" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdvancesFromFederalHomeLoanBanks_a30e88c2-905d-4820-820d-1eaec9696d26" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdvancesFromFederalHomeLoanBanks"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e41de743-852f-4f8f-9bce-a7131c6ee7d7" xlink:to="loc_us-gaap_AdvancesFromFederalHomeLoanBanks_a30e88c2-905d-4820-820d-1eaec9696d26" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_FederalReserveBankBorrowings_8b848dc7-4710-4952-afef-d9c0856ce00c" xlink:href="gbci-20230331.xsd#gbci_FederalReserveBankBorrowings"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e41de743-852f-4f8f-9bce-a7131c6ee7d7" xlink:to="loc_gbci_FederalReserveBankBorrowings_8b848dc7-4710-4952-afef-d9c0856ce00c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecurities_c608bade-f0e7-4412-9011-f0377d16ce5f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecurities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_0d18cf7c-e8ab-486d-87ce-d151ac960c7f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecurities_c608bade-f0e7-4412-9011-f0377d16ce5f" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_0d18cf7c-e8ab-486d-87ce-d151ac960c7f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_acdd561f-70c7-49e8-97f5-96f375575282" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecurities_c608bade-f0e7-4412-9011-f0377d16ce5f" xlink:to="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_acdd561f-70c7-49e8-97f5-96f375575282" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_f9fc2764-92d4-4b58-8621-8149931195b0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_557d693a-4ff5-4dba-b36f-0dc04d53f808" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_f9fc2764-92d4-4b58-8621-8149931195b0" xlink:to="loc_us-gaap_PreferredStockValue_557d693a-4ff5-4dba-b36f-0dc04d53f808" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValueOutstanding_4441e803-b4bf-42f8-8243-87abac4ff718" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockValueOutstanding"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_f9fc2764-92d4-4b58-8621-8149931195b0" xlink:to="loc_us-gaap_CommonStockValueOutstanding_4441e803-b4bf-42f8-8243-87abac4ff718" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_d65daafc-0b5f-4a45-91c8-6e64d7ad0b90" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdditionalPaidInCapitalCommonStock"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_f9fc2764-92d4-4b58-8621-8149931195b0" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_d65daafc-0b5f-4a45-91c8-6e64d7ad0b90" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_53bcaed8-202c-49fc-b91c-0aacfbad0342" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_f9fc2764-92d4-4b58-8621-8149931195b0" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_53bcaed8-202c-49fc-b91c-0aacfbad0342" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_771f095b-97fd-4c96-a864-6742f3d66aad" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_f9fc2764-92d4-4b58-8621-8149931195b0" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_771f095b-97fd-4c96-a864-6742f3d66aad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsAndFederalFundsSold_bfa93a3f-c4d9-4c15-a5e7-608c28a6e9db" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsAndFederalFundsSold"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_CashCashEquivalentsAndFederalFundsSold_bfa93a3f-c4d9-4c15-a5e7-608c28a6e9db" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecurities_93768c0f-a63d-423c-92ac-75dac9a50b57" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecurities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_DebtSecurities_93768c0f-a63d-423c-92ac-75dac9a50b57" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup_f0369acd-f8d8-4402-a1cb-f27f3a5a7421" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroup_f0369acd-f8d8-4402-a1cb-f27f3a5a7421" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAfterAllowanceForCreditLoss_ce9f95e3-63be-4c5c-9e7e-58143429c774" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestAfterAllowanceForCreditLoss"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAfterAllowanceForCreditLoss_ce9f95e3-63be-4c5c-9e7e-58143429c774" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_PropertyPlantAndEquipmentAndLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_a47f3ec1-48e5-435f-82c9-3113cde73a23" xlink:href="gbci-20230331.xsd#gbci_PropertyPlantAndEquipmentAndLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_gbci_PropertyPlantAndEquipmentAndLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_a47f3ec1-48e5-435f-82c9-3113cde73a23" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherRealEstateAndForeclosedAssets_786d534f-f1dd-4478-820f-66d8ad4989a4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherRealEstateAndForeclosedAssets"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_OtherRealEstateAndForeclosedAssets_786d534f-f1dd-4478-820f-66d8ad4989a4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestReceivable_61fb11c9-412f-4444-8bc5-ad04cef2f5f7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestReceivable"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_InterestReceivable_61fb11c9-412f-4444-8bc5-ad04cef2f5f7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_6116601f-6fe2-4d7c-96e0-454b991a3b8e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_6116601f-6fe2-4d7c-96e0-454b991a3b8e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_21694d67-bc5c-4c37-b342-357899d4e25c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_Goodwill_21694d67-bc5c-4c37-b342-357899d4e25c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_NonmarketableSecuritiesEquitySecurities_670b35bb-9e32-443a-b9f3-d8ef888f066b" xlink:href="gbci-20230331.xsd#gbci_NonmarketableSecuritiesEquitySecurities"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_gbci_NonmarketableSecuritiesEquitySecurities_670b35bb-9e32-443a-b9f3-d8ef888f066b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BankOwnedLifeInsurance_72dd57ae-f0a8-419d-bff8-7fe34d621e47" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BankOwnedLifeInsurance"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_BankOwnedLifeInsurance_72dd57ae-f0a8-419d-bff8-7fe34d621e47" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssets_0284fca1-cbad-4c95-b989-9de77aedd70e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAssets"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_OtherAssets_0284fca1-cbad-4c95-b989-9de77aedd70e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxAssetsNet_f3b21ffb-e6e5-4e10-beaf-dc3bceee4968" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredIncomeTaxAssetsNet"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e6c5967e-b3b2-463e-bbbf-93d6368ff5f3" xlink:to="loc_us-gaap_DeferredIncomeTaxAssetsNet_f3b21ffb-e6e5-4e10-beaf-dc3bceee4968" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/UnauditedCondensedConsolidatedStatementsofOperations" xlink:type="simple" xlink:href="gbci-20230331.xsd#UnauditedCondensedConsolidatedStatementsofOperations"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/UnauditedCondensedConsolidatedStatementsofOperations" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_732509c8-1ebb-45a3-b9fb-d53e208541ab" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_69766860-1d22-4bb2-8a91-dea46309ba6c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_732509c8-1ebb-45a3-b9fb-d53e208541ab" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_69766860-1d22-4bb2-8a91-dea46309ba6c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_9290d9b0-8e4f-47a6-9c83-193d4a04252d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_732509c8-1ebb-45a3-b9fb-d53e208541ab" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_9290d9b0-8e4f-47a6-9c83-193d4a04252d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_7916e395-4355-40a8-974d-52ba64105722" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestIncomeExpenseNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperating_33902d7b-a655-42b2-a738-ce5c4485c0b5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestAndDividendIncomeOperating"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseNet_7916e395-4355-40a8-974d-52ba64105722" xlink:to="loc_us-gaap_InterestAndDividendIncomeOperating_33902d7b-a655-42b2-a738-ce5c4485c0b5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpense_606e8fbe-fdca-4909-be24-df0d87f48a48" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpense"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseNet_7916e395-4355-40a8-974d-52ba64105722" xlink:to="loc_us-gaap_InterestExpense_606e8fbe-fdca-4909-be24-df0d87f48a48" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_5874cfeb-d14b-4a6e-9244-f4993a197fa3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_8096e3db-81c2-4b65-b5cc-1c1b6659e556" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestIncomeExpenseNet"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_5874cfeb-d14b-4a6e-9244-f4993a197fa3" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_8096e3db-81c2-4b65-b5cc-1c1b6659e556" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_91d326d0-4911-416d-824a-6c5785d59251" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProvisionForLoanLeaseAndOtherLosses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_5874cfeb-d14b-4a6e-9244-f4993a197fa3" xlink:to="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_91d326d0-4911-416d-824a-6c5785d59251" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpense_64b740d7-3d48-459c-9ce8-485a320c0682" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpense"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDeposits_ed5ee593-75a9-4130-9e50-0918b44b5bba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpenseDeposits"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpense_64b740d7-3d48-459c-9ce8-485a320c0682" xlink:to="loc_us-gaap_InterestExpenseDeposits_ed5ee593-75a9-4130-9e50-0918b44b5bba" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseJuniorSubordinatedDebentures_a789aecd-986a-42fc-b742-23fbecc7ee89" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpenseJuniorSubordinatedDebentures"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpense_64b740d7-3d48-459c-9ce8-485a320c0682" xlink:to="loc_us-gaap_InterestExpenseJuniorSubordinatedDebentures_a789aecd-986a-42fc-b742-23fbecc7ee89" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_InterestExpenseFederalReserveBank_6383626b-b13f-4d71-97bb-95ed5ef79eac" xlink:href="gbci-20230331.xsd#gbci_InterestExpenseFederalReserveBank"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpense_64b740d7-3d48-459c-9ce8-485a320c0682" xlink:to="loc_gbci_InterestExpenseFederalReserveBank_6383626b-b13f-4d71-97bb-95ed5ef79eac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_InterestExpenseFederalHomeLoanBankAdvance_ac89a9d0-d780-4814-acca-7dad487364fb" xlink:href="gbci-20230331.xsd#gbci_InterestExpenseFederalHomeLoanBankAdvance"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpense_64b740d7-3d48-459c-9ce8-485a320c0682" xlink:to="loc_gbci_InterestExpenseFederalHomeLoanBankAdvance_ac89a9d0-d780-4814-acca-7dad487364fb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseOther_7783ce03-4986-4825-be9f-8a4dc325aa70" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpenseOther"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpense_64b740d7-3d48-459c-9ce8-485a320c0682" xlink:to="loc_us-gaap_InterestExpenseOther_7783ce03-4986-4825-be9f-8a4dc325aa70" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseSecuritiesSoldUnderAgreementsToRepurchase_cf23070c-4b88-433c-8b76-e6255e957adc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpenseSecuritiesSoldUnderAgreementsToRepurchase"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpense_64b740d7-3d48-459c-9ce8-485a320c0682" xlink:to="loc_us-gaap_InterestExpenseSecuritiesSoldUnderAgreementsToRepurchase_cf23070c-4b88-433c-8b76-e6255e957adc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_586ce0e1-77e0-4270-a895-dd81e23a28e0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_c6176599-bfd9-41e3-bc81-1f4c1a49063e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_586ce0e1-77e0-4270-a895-dd81e23a28e0" xlink:to="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_c6176599-bfd9-41e3-bc81-1f4c1a49063e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestIncome_6805b8c8-2fa3-480c-9a16-85b61f529b26" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_586ce0e1-77e0-4270-a895-dd81e23a28e0" xlink:to="loc_us-gaap_NoninterestIncome_6805b8c8-2fa3-480c-9a16-85b61f529b26" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestExpense_a8942c98-ed9d-4d6d-9497-1cbef45d29f6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestExpense"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_586ce0e1-77e0-4270-a895-dd81e23a28e0" xlink:to="loc_us-gaap_NoninterestExpense_a8942c98-ed9d-4d6d-9497-1cbef45d29f6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestExpense_f2bdff85-e03f-4cde-88b1-fbdef7ff5433" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestExpense"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LaborAndRelatedExpense_796482d7-42b5-411e-a8a4-76ff3eda9220" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LaborAndRelatedExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_f2bdff85-e03f-4cde-88b1-fbdef7ff5433" xlink:to="loc_us-gaap_LaborAndRelatedExpense_796482d7-42b5-411e-a8a4-76ff3eda9220" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OccupancyNet_23c51e86-4678-4e5e-9412-4c9684dca220" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OccupancyNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_f2bdff85-e03f-4cde-88b1-fbdef7ff5433" xlink:to="loc_us-gaap_OccupancyNet_23c51e86-4678-4e5e-9412-4c9684dca220" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdvertisingExpense_97753bf3-c365-4bb2-9a64-ba6826646191" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdvertisingExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_f2bdff85-e03f-4cde-88b1-fbdef7ff5433" xlink:to="loc_us-gaap_AdvertisingExpense_97753bf3-c365-4bb2-9a64-ba6826646191" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InformationTechnologyAndDataProcessing_408b6d3c-93ca-4357-ad6f-707243774517" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InformationTechnologyAndDataProcessing"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_f2bdff85-e03f-4cde-88b1-fbdef7ff5433" xlink:to="loc_us-gaap_InformationTechnologyAndDataProcessing_408b6d3c-93ca-4357-ad6f-707243774517" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeclosedRealEstateExpense_d5d819d0-7d17-4cac-85ee-4a409b2e2cc2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ForeclosedRealEstateExpense"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_f2bdff85-e03f-4cde-88b1-fbdef7ff5433" xlink:to="loc_us-gaap_ForeclosedRealEstateExpense_d5d819d0-7d17-4cac-85ee-4a409b2e2cc2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_GeneralInsuranceAndFederalDepositInsuranceCorporationPremiumExpense_4849d681-b864-474a-a3e5-e4bd56b8ccd7" xlink:href="gbci-20230331.xsd#gbci_GeneralInsuranceAndFederalDepositInsuranceCorporationPremiumExpense"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_f2bdff85-e03f-4cde-88b1-fbdef7ff5433" xlink:to="loc_gbci_GeneralInsuranceAndFederalDepositInsuranceCorporationPremiumExpense_4849d681-b864-474a-a3e5-e4bd56b8ccd7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_d8ed6fed-7153-4e39-8e1e-4925e89bde2c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_f2bdff85-e03f-4cde-88b1-fbdef7ff5433" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_d8ed6fed-7153-4e39-8e1e-4925e89bde2c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoninterestExpense_9d7dad5f-0120-4767-84d0-30130afd0678" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherNoninterestExpense"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_f2bdff85-e03f-4cde-88b1-fbdef7ff5433" xlink:to="loc_us-gaap_OtherNoninterestExpense_9d7dad5f-0120-4767-84d0-30130afd0678" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestIncome_b4a4220d-9365-4ecd-9807-478747d093c9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_ServiceChargesAndOtherFees_4736df8e-f245-4c67-9f38-6450af435cf0" xlink:href="gbci-20230331.xsd#gbci_ServiceChargesAndOtherFees"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_b4a4220d-9365-4ecd-9807-478747d093c9" xlink:to="loc_gbci_ServiceChargesAndOtherFees_4736df8e-f245-4c67-9f38-6450af435cf0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_MiscellaneousLoanFeesAndCharges_8e70608d-457b-433b-8472-0d82528d6f9e" xlink:href="gbci-20230331.xsd#gbci_MiscellaneousLoanFeesAndCharges"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_b4a4220d-9365-4ecd-9807-478747d093c9" xlink:to="loc_gbci_MiscellaneousLoanFeesAndCharges_8e70608d-457b-433b-8472-0d82528d6f9e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnSalesOfLoansNet_8b54e30f-dc49-428c-b120-47dc7baebda5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainLossOnSalesOfLoansNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_b4a4220d-9365-4ecd-9807-478747d093c9" xlink:to="loc_us-gaap_GainLossOnSalesOfLoansNet_8b54e30f-dc49-428c-b120-47dc7baebda5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesRealizedGainLoss_d2e22dc4-3339-4c92-9573-ac0d1a44cfc3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesRealizedGainLoss"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_b4a4220d-9365-4ecd-9807-478747d093c9" xlink:to="loc_us-gaap_DebtSecuritiesRealizedGainLoss_d2e22dc4-3339-4c92-9573-ac0d1a44cfc3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoninterestIncomeOtherOperatingIncome_5d666f5a-9742-44a2-8f4f-6c6d56df631d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NoninterestIncomeOtherOperatingIncome"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_b4a4220d-9365-4ecd-9807-478747d093c9" xlink:to="loc_us-gaap_NoninterestIncomeOtherOperatingIncome_5d666f5a-9742-44a2-8f4f-6c6d56df631d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperating_9d4bb0bc-44bd-4796-ba18-3185db9202fc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestAndDividendIncomeOperating"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeSecurities_72d8c7ff-39db-4888-86a0-5c77a8646ff7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestAndDividendIncomeSecurities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating_9d4bb0bc-44bd-4796-ba18-3185db9202fc" xlink:to="loc_us-gaap_InterestAndDividendIncomeSecurities_72d8c7ff-39db-4888-86a0-5c77a8646ff7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndFeeIncomeLoansConsumerRealEstate_79859fff-81d6-4f23-9ac7-0ef21701db21" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestAndFeeIncomeLoansConsumerRealEstate"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating_9d4bb0bc-44bd-4796-ba18-3185db9202fc" xlink:to="loc_us-gaap_InterestAndFeeIncomeLoansConsumerRealEstate_79859fff-81d6-4f23-9ac7-0ef21701db21" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndFeeIncomeLoansCommercial_9ebb3824-3410-4d41-9e62-4692ac89c399" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestAndFeeIncomeLoansCommercial"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating_9d4bb0bc-44bd-4796-ba18-3185db9202fc" xlink:to="loc_us-gaap_InterestAndFeeIncomeLoansCommercial_9ebb3824-3410-4d41-9e62-4692ac89c399" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndFeeIncomeLoansOtherConsumer_5d4f18bc-cbc6-4cef-aa37-2a4a1af82618" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestAndFeeIncomeLoansOtherConsumer"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating_9d4bb0bc-44bd-4796-ba18-3185db9202fc" xlink:to="loc_us-gaap_InterestAndFeeIncomeLoansOtherConsumer_5d4f18bc-cbc6-4cef-aa37-2a4a1af82618" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/UnauditedCondensedConsolidatedStatementsofComprehensiveLossIncome" xlink:type="simple" xlink:href="gbci-20230331.xsd#UnauditedCondensedConsolidatedStatementsofComprehensiveLossIncome"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/UnauditedCondensedConsolidatedStatementsofComprehensiveLossIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_a3dc0c15-3a5f-4295-9a5f-af9fdb86bc36" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_e5a1b8d6-6f2b-428d-abd8-ee5bbfb8a95e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_a3dc0c15-3a5f-4295-9a5f-af9fdb86bc36" xlink:to="loc_us-gaap_NetIncomeLoss_e5a1b8d6-6f2b-428d-abd8-ee5bbfb8a95e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_d8e68114-5eaf-4e31-bf99-3842d0a65ea0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_a3dc0c15-3a5f-4295-9a5f-af9fdb86bc36" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_d8e68114-5eaf-4e31-bf99-3842d0a65ea0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_c7a0d4c8-cc88-4f39-b703-bc3a6b7a42c4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax_f580cf42-b7d0-4fe0-a7bf-3f2565ea7033" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_c7a0d4c8-cc88-4f39-b703-bc3a6b7a42c4" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax_f580cf42-b7d0-4fe0-a7bf-3f2565ea7033" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesBeforeTax_81339cd6-89d6-4753-9519-79ded0752b75" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesBeforeTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_c7a0d4c8-cc88-4f39-b703-bc3a6b7a42c4" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesBeforeTax_81339cd6-89d6-4753-9519-79ded0752b75" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OciDebtSecuritiesAvailableForSaleTransferToHeldToMaturityAdjustmentFromAociForAmortizationOfGainLossBeforeTax_b5e89c17-7668-4438-946b-3d0c98d5f7a8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OciDebtSecuritiesAvailableForSaleTransferToHeldToMaturityAdjustmentFromAociForAmortizationOfGainLossBeforeTax"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_c7a0d4c8-cc88-4f39-b703-bc3a6b7a42c4" xlink:to="loc_us-gaap_OciDebtSecuritiesAvailableForSaleTransferToHeldToMaturityAdjustmentFromAociForAmortizationOfGainLossBeforeTax_b5e89c17-7668-4438-946b-3d0c98d5f7a8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax_0b8adf79-e453-45e1-a30c-e592ca65ef9d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_c7a0d4c8-cc88-4f39-b703-bc3a6b7a42c4" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax_0b8adf79-e453-45e1-a30c-e592ca65ef9d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_9567eeb8-f418-413a-8355-111caef0111d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_78e246de-9537-4273-8284-68430c5a803e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_9567eeb8-f418-413a-8355-111caef0111d" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_78e246de-9537-4273-8284-68430c5a803e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_922218e4-7f23-4455-82e7-580965850780" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_9567eeb8-f418-413a-8355-111caef0111d" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_922218e4-7f23-4455-82e7-580965850780" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_1940e81a-5aef-406d-b204-98121cbc0180" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax_b942d029-0dab-4cc6-9284-f46121865b59" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_1940e81a-5aef-406d-b204-98121cbc0180" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax_b942d029-0dab-4cc6-9284-f46121865b59" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax_c22d0333-ae94-4647-93a8-69be01db0edc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_1940e81a-5aef-406d-b204-98121cbc0180" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationTax_c22d0333-ae94-4647-93a8-69be01db0edc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeReclassificationForDiscontinuanceBeforeTax_e225fb88-eb37-4ea1-bd35-75437e3ea52c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeReclassificationForDiscontinuanceBeforeTax"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTax_1940e81a-5aef-406d-b204-98121cbc0180" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeReclassificationForDiscontinuanceBeforeTax_e225fb88-eb37-4ea1-bd35-75437e3ea52c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/UnauditedCondensedConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="gbci-20230331.xsd#UnauditedCondensedConsolidatedStatementsofCashFlows"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/UnauditedCondensedConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_8aa75eab-b4db-4255-8081-fbccf92f12a9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_356053a1-648a-48fe-9cd2-9773dfcef161" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_8aa75eab-b4db-4255-8081-fbccf92f12a9" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_356053a1-648a-48fe-9cd2-9773dfcef161" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_27b2534d-4183-4258-a380-ffd2ca1a6b29" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_8aa75eab-b4db-4255-8081-fbccf92f12a9" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_27b2534d-4183-4258-a380-ffd2ca1a6b29" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_158e5d80-fcc9-479d-b543-ea6733bf39d2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_8aa75eab-b4db-4255-8081-fbccf92f12a9" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_158e5d80-fcc9-479d-b543-ea6733bf39d2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_94ab663e-3bfc-4a1b-97e2-6ce8889e0725" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInDeposits_a102bb85-58c7-454c-ac48-64d0415bf8ec" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInDeposits"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_94ab663e-3bfc-4a1b-97e2-6ce8889e0725" xlink:to="loc_us-gaap_IncreaseDecreaseInDeposits_a102bb85-58c7-454c-ac48-64d0415bf8ec" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPaymentsForInSecuritiesSoldUnderAgreementsToRepurchase_d13ac739-41a5-4510-a018-d3f20c617c74" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromPaymentsForInSecuritiesSoldUnderAgreementsToRepurchase"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_94ab663e-3bfc-4a1b-97e2-6ce8889e0725" xlink:to="loc_us-gaap_ProceedsFromPaymentsForInSecuritiesSoldUnderAgreementsToRepurchase_d13ac739-41a5-4510-a018-d3f20c617c74" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromRepaymentsOfShortTermDebtMaturingInThreeMonthsOrLess_6741de7b-395a-49ae-83d0-bed17f4247ce" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromRepaymentsOfShortTermDebtMaturingInThreeMonthsOrLess"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_94ab663e-3bfc-4a1b-97e2-6ce8889e0725" xlink:to="loc_us-gaap_ProceedsFromRepaymentsOfShortTermDebtMaturingInThreeMonthsOrLess_6741de7b-395a-49ae-83d0-bed17f4247ce" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromRepaymentsOfOtherDebt_c4363351-fe8a-4563-94f6-4998ed5d2d69" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromRepaymentsOfOtherDebt"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_94ab663e-3bfc-4a1b-97e2-6ce8889e0725" xlink:to="loc_us-gaap_ProceedsFromRepaymentsOfOtherDebt_c4363351-fe8a-4563-94f6-4998ed5d2d69" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsCommonStock_9a0f6c48-11d5-461b-bc40-e77f159b0786" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsOfDividendsCommonStock"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_94ab663e-3bfc-4a1b-97e2-6ce8889e0725" xlink:to="loc_us-gaap_PaymentsOfDividendsCommonStock_9a0f6c48-11d5-461b-bc40-e77f159b0786" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_93c7beb4-393d-4265-b169-14d8aa850213" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_94ab663e-3bfc-4a1b-97e2-6ce8889e0725" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_93c7beb4-393d-4265-b169-14d8aa850213" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_e1d34c7d-6277-45a3-9541-9dc6953ae449" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_94ab663e-3bfc-4a1b-97e2-6ce8889e0725" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_e1d34c7d-6277-45a3-9541-9dc6953ae449" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_2dfb25c0-51d1-460f-8431-f975cf2600bb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_2dfb25c0-51d1-460f-8431-f975cf2600bb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_edad7cdd-745b-4b35-9eb1-c12647170a27" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_edad7cdd-745b-4b35-9eb1-c12647170a27" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities_4afded01-c5d1-4df2-adc8-862e48e9f0d4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities_4afded01-c5d1-4df2-adc8-862e48e9f0d4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireHeldToMaturitySecurities_9a6717f0-b95b-4ee6-bd2d-05815bf9da2b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireHeldToMaturitySecurities"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_PaymentsToAcquireHeldToMaturitySecurities_9a6717f0-b95b-4ee6-bd2d-05815bf9da2b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromLoanAndLeaseOriginationsAndPrincipalCollections1_58eb8e07-6ee3-45f3-8e6f-1beb2f2baa9b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromLoanAndLeaseOriginationsAndPrincipalCollections1"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_ProceedsFromLoanAndLeaseOriginationsAndPrincipalCollections1_58eb8e07-6ee3-45f3-8e6f-1beb2f2baa9b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_PaymentsForLoansOriginatedOrAcquired_56b8db45-179b-4507-ab8c-67c2c4734236" xlink:href="gbci-20230331.xsd#gbci_PaymentsForLoansOriginatedOrAcquired"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_gbci_PaymentsForLoansOriginatedOrAcquired_56b8db45-179b-4507-ab8c-67c2c4734236" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromProductiveAssets_5636233f-275c-41dd-8750-e9ecd944e552" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsForProceedsFromProductiveAssets"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_PaymentsForProceedsFromProductiveAssets_5636233f-275c-41dd-8750-e9ecd944e552" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfWhollyOwnedRealEstateAndRealEstateAcquiredInSettlementOfLoans_d5fa786c-284e-4efb-87b2-3f9f966e3158" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromSaleOfWhollyOwnedRealEstateAndRealEstateAcquiredInSettlementOfLoans"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_ProceedsFromSaleOfWhollyOwnedRealEstateAndRealEstateAcquiredInSettlementOfLoans_d5fa786c-284e-4efb-87b2-3f9f966e3158" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfFederalHomeLoanBankStock_459b5a72-6110-40e7-a123-6a70d4f53820" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromSaleOfFederalHomeLoanBankStock"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_ProceedsFromSaleOfFederalHomeLoanBankStock_459b5a72-6110-40e7-a123-6a70d4f53820" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireFederalHomeLoanBankStock_ea8d6d22-b39e-4b94-a5ae-bfc86b3930d2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireFederalHomeLoanBankStock"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_PaymentsToAcquireFederalHomeLoanBankStock_ea8d6d22-b39e-4b94-a5ae-bfc86b3930d2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromLifeInsurancePolicies_8fb96955-7768-49b8-afe8-a2d57bf56fc7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromLifeInsurancePolicies"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_ProceedsFromLifeInsurancePolicies_8fb96955-7768-49b8-afe8-a2d57bf56fc7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireOtherInvestments_9875a930-406f-4440-9902-ee4809bd476e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireOtherInvestments"/>
    <link:calculationArc order="12" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_PaymentsToAcquireOtherInvestments_9875a930-406f-4440-9902-ee4809bd476e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_d4b59762-adcf-48d7-a4f2-d0793088f608" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ebdd57a4-062a-4c59-be1a-5fdac1280690" xlink:to="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_d4b59762-adcf-48d7-a4f2-d0793088f608" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_1a99c2bf-db3e-459a-b2e2-ca7c8f2feb94" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_NetIncomeLoss_1a99c2bf-db3e-459a-b2e2-ca7c8f2feb94" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_507ed9b1-ef32-49c6-83f6-154f78092002" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProvisionForLoanLeaseAndOtherLosses"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_507ed9b1-ef32-49c6-83f6-154f78092002" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments_45347033-8fb5-4f4d-807b-e5be30fd6da7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments_45347033-8fb5-4f4d-807b-e5be30fd6da7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_AccretionAmortizationOfDiscountsAndPremiumsBusinessCombinations_fc6b33ba-42ae-47b2-ae91-17d4c88ebd9f" xlink:href="gbci-20230331.xsd#gbci_AccretionAmortizationOfDiscountsAndPremiumsBusinessCombinations"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_gbci_AccretionAmortizationOfDiscountsAndPremiumsBusinessCombinations_fc6b33ba-42ae-47b2-ae91-17d4c88ebd9f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForOriginationAndPurchasesOfLoansHeldForSale_81aaaf5d-c6fa-4d3f-a4c4-24713974868b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsForOriginationAndPurchasesOfLoansHeldForSale"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_PaymentsForOriginationAndPurchasesOfLoansHeldForSale_81aaaf5d-c6fa-4d3f-a4c4-24713974868b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfMortgageLoansHeldForSale_bb004c33-87b0-463a-999c-260616722082" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromSaleOfMortgageLoansHeldForSale"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_ProceedsFromSaleOfMortgageLoansHeldForSale_bb004c33-87b0-463a-999c-260616722082" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnSalesOfLoansNet_87fdfaee-1a74-4dd2-8d41-de441fb8aa0f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainLossOnSalesOfLoansNet"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_GainLossOnSalesOfLoansNet_87fdfaee-1a74-4dd2-8d41-de441fb8aa0f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnSaleOfInvestments_de688f92-b4a0-41c2-a41b-900bcb505da6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainLossOnSaleOfInvestments"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_GainLossOnSaleOfInvestments_de688f92-b4a0-41c2-a41b-900bcb505da6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LifeInsuranceCorporateOrBankOwnedChangeInValue_593ffd64-35d8-4981-bb7e-905082267c11" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LifeInsuranceCorporateOrBankOwnedChangeInValue"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_LifeInsuranceCorporateOrBankOwnedChangeInValue_593ffd64-35d8-4981-bb7e-905082267c11" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_3d7bb2e6-d60e-4509-adf5-ee5326ec6102" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_ShareBasedCompensation_3d7bb2e6-d60e-4509-adf5-ee5326ec6102" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationNonproduction_4a6dced4-d918-4018-bbf5-33a2ddd5b4a7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DepreciationNonproduction"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_DepreciationNonproduction_4a6dced4-d918-4018-bbf5-33a2ddd5b4a7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_e04ece85-c626-4084-9b29-7b56f7fa5495" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_e04ece85-c626-4084-9b29-7b56f7fa5495" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_VariableInterestEntitiesInvestmentAmortization_76f80d7e-d82e-49a1-acd1-ac8bc7c744a4" xlink:href="gbci-20230331.xsd#gbci_VariableInterestEntitiesInvestmentAmortization"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_gbci_VariableInterestEntitiesInvestmentAmortization_76f80d7e-d82e-49a1-acd1-ac8bc7c744a4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet_7decc443-4316-4616-beec-994173a9a44a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet"/>
    <link:calculationArc order="14" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet_7decc443-4316-4616-beec-994173a9a44a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_bab80d1c-280e-42af-83b2-2a83df4f301a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:calculationArc order="15" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_bab80d1c-280e-42af-83b2-2a83df4f301a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInterestPayableNet_356ffbf3-17f3-4f22-8c62-52c38a68bb2a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInInterestPayableNet"/>
    <link:calculationArc order="16" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_IncreaseDecreaseInInterestPayableNet_356ffbf3-17f3-4f22-8c62-52c38a68bb2a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_b876da27-bdad-478c-9036-27b1a30ea1fc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities"/>
    <link:calculationArc order="17" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_b876da27-bdad-478c-9036-27b1a30ea1fc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_c4ac83b4-c13f-492b-a6bd-146f9f6dde8f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainsLossesOnSalesOfOtherRealEstate"/>
    <link:calculationArc order="18" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_dd9162a5-843e-4b81-9ba3-28e6bb2b0898" xlink:to="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_c4ac83b4-c13f-492b-a6bd-146f9f6dde8f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/NatureofOperationsandSummaryofSignificantAccountingPoliciesDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#NatureofOperationsandSummaryofSignificantAccountingPoliciesDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/NatureofOperationsandSummaryofSignificantAccountingPoliciesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_b4d2844f-576f-4916-962a-346e91ffa96e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProvisionForLoanLeaseAndOtherLosses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OffBalanceSheetCreditLossLiabilityCreditLossExpenseReversal_8f0b81c5-483b-42b6-960b-293f8831dc12" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OffBalanceSheetCreditLossLiabilityCreditLossExpenseReversal"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_b4d2844f-576f-4916-962a-346e91ffa96e" xlink:to="loc_us-gaap_OffBalanceSheetCreditLossLiabilityCreditLossExpenseReversal_8f0b81c5-483b-42b6-960b-293f8831dc12" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLossesExpensed_ad601057-4906-4b45-84a9-ace27cfcba06" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProvisionForLoanLossesExpensed"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_b4d2844f-576f-4916-962a-346e91ffa96e" xlink:to="loc_us-gaap_ProvisionForLoanLossesExpensed_ad601057-4906-4b45-84a9-ace27cfcba06" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/DebtSecuritiesAmortizedCostGrossUnrealizedGainsandLossesandFairValueofInvestmentSecuritiesDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#DebtSecuritiesAmortizedCostGrossUnrealizedGainsandLossesandFairValueofInvestmentSecuritiesDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/DebtSecuritiesAmortizedCostGrossUnrealizedGainsandLossesandFairValueofInvestmentSecuritiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_bc809999-55a8-4e3b-a4f5-8ad439c63819" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesFairValue_349ddac1-82c9-4f86-9c5a-73d5945502c9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesFairValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_bc809999-55a8-4e3b-a4f5-8ad439c63819" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesFairValue_349ddac1-82c9-4f86-9c5a-73d5945502c9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss_f95d0666-2adc-466f-a33a-1eee50e7d344" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_bc809999-55a8-4e3b-a4f5-8ad439c63819" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss_f95d0666-2adc-466f-a33a-1eee50e7d344" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain_5542e1a3-e1d2-400e-bd24-91fec424e908" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_bc809999-55a8-4e3b-a4f5-8ad439c63819" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain_5542e1a3-e1d2-400e-bd24-91fec424e908" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_SecuritiesGrossUnrealizedGainAccumulatedInInvestments_3b04b5d3-d102-448e-b387-f181aedb26a1" xlink:href="gbci-20230331.xsd#gbci_SecuritiesGrossUnrealizedGainAccumulatedInInvestments"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain_d9f13428-0126-4c00-a19d-f60e706bbe81" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_SecuritiesGrossUnrealizedGainAccumulatedInInvestments_3b04b5d3-d102-448e-b387-f181aedb26a1" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain_d9f13428-0126-4c00-a19d-f60e706bbe81" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_240aebdf-2fb9-4e9b-9d1a-03c104e43b6b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_SecuritiesGrossUnrealizedGainAccumulatedInInvestments_3b04b5d3-d102-448e-b387-f181aedb26a1" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_240aebdf-2fb9-4e9b-9d1a-03c104e43b6b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_SecuritiesGrossUnrealizedLossAccumulatedInInvestments_55d0c783-bb0e-4616-84d3-d4a9bba14bd0" xlink:href="gbci-20230331.xsd#gbci_SecuritiesGrossUnrealizedLossAccumulatedInInvestments"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss_5274f42b-c7f8-4b82-a96e-236794f8ff59" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_SecuritiesGrossUnrealizedLossAccumulatedInInvestments_55d0c783-bb0e-4616-84d3-d4a9bba14bd0" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss_5274f42b-c7f8-4b82-a96e-236794f8ff59" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_890e30d0-bafb-4142-b2e3-fde02dd0613f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_SecuritiesGrossUnrealizedLossAccumulatedInInvestments_55d0c783-bb0e-4616-84d3-d4a9bba14bd0" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_890e30d0-bafb-4142-b2e3-fde02dd0613f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_DebtSecuritiesFairValue_ef2dfe20-3bcf-44be-8d6a-5c58e6c5b2cc" xlink:href="gbci-20230331.xsd#gbci_DebtSecuritiesFairValue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_70ecbfbf-d2a0-4405-abdf-a311c5080773" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_DebtSecuritiesFairValue_ef2dfe20-3bcf-44be-8d6a-5c58e6c5b2cc" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_70ecbfbf-d2a0-4405-abdf-a311c5080773" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesFairValue_746d8546-2768-453c-8e08-f2e9ccf9f5bc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_DebtSecuritiesFairValue_ef2dfe20-3bcf-44be-8d6a-5c58e6c5b2cc" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesFairValue_746d8546-2768-453c-8e08-f2e9ccf9f5bc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss_683747fe-cf0e-4359-b77d-4033d70d62d8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_71308f24-becf-46b0-963b-746c902fc71a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss_683747fe-cf0e-4359-b77d-4033d70d62d8" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_71308f24-becf-46b0-963b-746c902fc71a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_3310e961-c31d-4e25-a0c9-aea2144b802e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss_683747fe-cf0e-4359-b77d-4033d70d62d8" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_3310e961-c31d-4e25-a0c9-aea2144b802e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_2a06d85f-e32b-45f1-90fe-b4f34414fb9c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss_683747fe-cf0e-4359-b77d-4033d70d62d8" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_2a06d85f-e32b-45f1-90fe-b4f34414fb9c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_DebtSecuritiesAmortizedCostBasis_d8c0746f-ca16-4e56-a96e-89b374f5afac" xlink:href="gbci-20230331.xsd#gbci_DebtSecuritiesAmortizedCostBasis"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_SecuritiesGrossUnrealizedGainAccumulatedInInvestments_6d83e07a-3da3-4429-840d-1a07f7e8f172" xlink:href="gbci-20230331.xsd#gbci_SecuritiesGrossUnrealizedGainAccumulatedInInvestments"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_DebtSecuritiesAmortizedCostBasis_d8c0746f-ca16-4e56-a96e-89b374f5afac" xlink:to="loc_gbci_SecuritiesGrossUnrealizedGainAccumulatedInInvestments_6d83e07a-3da3-4429-840d-1a07f7e8f172" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_DebtSecuritiesFairValue_49ebb07a-87c1-4d69-ac8f-391f4cdaf7d8" xlink:href="gbci-20230331.xsd#gbci_DebtSecuritiesFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_DebtSecuritiesAmortizedCostBasis_d8c0746f-ca16-4e56-a96e-89b374f5afac" xlink:to="loc_gbci_DebtSecuritiesFairValue_49ebb07a-87c1-4d69-ac8f-391f4cdaf7d8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_SecuritiesGrossUnrealizedLossAccumulatedInInvestments_95475997-57a4-45a6-8e10-c56f4a8aa917" xlink:href="gbci-20230331.xsd#gbci_SecuritiesGrossUnrealizedLossAccumulatedInInvestments"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_DebtSecuritiesAmortizedCostBasis_d8c0746f-ca16-4e56-a96e-89b374f5afac" xlink:to="loc_gbci_SecuritiesGrossUnrealizedLossAccumulatedInInvestments_95475997-57a4-45a6-8e10-c56f4a8aa917" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/DebtSecuritiesAmortizedCostGrossUnrealizedGainsandLossesandFairValueofInvestmentSecuritiesDetails_1" xlink:type="simple" xlink:href="gbci-20230331.xsd#DebtSecuritiesAmortizedCostGrossUnrealizedGainsandLossesandFairValueofInvestmentSecuritiesDetails_1"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/DebtSecuritiesAmortizedCostGrossUnrealizedGainsandLossesandFairValueofInvestmentSecuritiesDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_gbci_DebtSecuritiesAmortizedCostBasis_bafba15c-6b25-40b2-9e66-574c077ed35e" xlink:href="gbci-20230331.xsd#gbci_DebtSecuritiesAmortizedCostBasis"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_2d8d3ea3-0e19-4c35-9d2d-efa0cb1739e6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_DebtSecuritiesAmortizedCostBasis_bafba15c-6b25-40b2-9e66-574c077ed35e" xlink:to="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_2d8d3ea3-0e19-4c35-9d2d-efa0cb1739e6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss_f37d8442-5ca3-440e-95c1-1b78d012709b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_DebtSecuritiesAmortizedCostBasis_bafba15c-6b25-40b2-9e66-574c077ed35e" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss_f37d8442-5ca3-440e-95c1-1b78d012709b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/DebtSecuritiesMaturityScheduleDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#DebtSecuritiesMaturityScheduleDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/DebtSecuritiesMaturityScheduleDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_765254cb-581f-444f-9eb7-47347b8c143b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesNextRollingTwelveMonthsFairValue_e080a37d-860c-40d2-a5f3-0c83156c06af" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesNextRollingTwelveMonthsFairValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_765254cb-581f-444f-9eb7-47347b8c143b" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesNextRollingTwelveMonthsFairValue_e080a37d-860c-40d2-a5f3-0c83156c06af" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearTwoThroughFiveFairValue_70767cb0-9b4c-4836-8d48-5487de59e521" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearTwoThroughFiveFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_765254cb-581f-444f-9eb7-47347b8c143b" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearTwoThroughFiveFairValue_70767cb0-9b4c-4836-8d48-5487de59e521" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearSixThroughTenFairValue_b1209488-658e-4017-a773-eb513566e189" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearSixThroughTenFairValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_765254cb-581f-444f-9eb7-47347b8c143b" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearSixThroughTenFairValue_b1209488-658e-4017-a773-eb513566e189" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingAfterYearTenFairValue_0e824deb-afaa-4025-af39-854f8c7b3fb3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingAfterYearTenFairValue"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_765254cb-581f-444f-9eb7-47347b8c143b" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingAfterYearTenFairValue_0e824deb-afaa-4025-af39-854f8c7b3fb3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_9e67e7fd-40e4-4e3c-abce-e2fab9364cda" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityWithoutSingleMaturityDate_519d9641-264c-4135-a2b0-cfced764cf6f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityWithoutSingleMaturityDate"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_9e67e7fd-40e4-4e3c-abce-e2fab9364cda" xlink:to="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityWithoutSingleMaturityDate_519d9641-264c-4135-a2b0-cfced764cf6f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDate_c394b34f-080d-4bb9-92f8-42eb8128c009" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDate"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesHeldToMaturityExcludingAccruedInterestBeforeAllowanceForCreditLoss_9e67e7fd-40e4-4e3c-abce-e2fab9364cda" xlink:to="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDate_c394b34f-080d-4bb9-92f8-42eb8128c009" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss_d770a852-2fa7-4e33-b3c7-f771544f925f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_4e78aa97-56fa-4b4c-aaa9-a294de9bcec3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss_d770a852-2fa7-4e33-b3c7-f771544f925f" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_4e78aa97-56fa-4b4c-aaa9-a294de9bcec3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateAmortizedCost_0cd4f5c2-4de0-48ff-a06d-cb363d70e0c7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateAmortizedCost"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestBeforeAllowanceForCreditLoss_d770a852-2fa7-4e33-b3c7-f771544f925f" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateAmortizedCost_0cd4f5c2-4de0-48ff-a06d-cb363d70e0c7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesSingleMaturityDateFairValue_3741f5eb-982c-43cf-a211-ed1ceecc39d1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesSingleMaturityDateFairValue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesNextRollingTwelveMonthsFairValue_fd1a0b40-dd4a-4053-93b6-8abc56d88e2e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesNextRollingTwelveMonthsFairValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesSingleMaturityDateFairValue_3741f5eb-982c-43cf-a211-ed1ceecc39d1" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesNextRollingTwelveMonthsFairValue_fd1a0b40-dd4a-4053-93b6-8abc56d88e2e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesRollingYearTwoThroughFiveFairValue_d6b1b909-c200-4ff2-a362-92fa7f435d83" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesRollingYearTwoThroughFiveFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesSingleMaturityDateFairValue_3741f5eb-982c-43cf-a211-ed1ceecc39d1" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesRollingYearTwoThroughFiveFairValue_d6b1b909-c200-4ff2-a362-92fa7f435d83" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesRollingYearSixThroughTenFairValue_df2b321b-e6da-4305-a91e-92dbfbc5b165" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesRollingYearSixThroughTenFairValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesSingleMaturityDateFairValue_3741f5eb-982c-43cf-a211-ed1ceecc39d1" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesRollingYearSixThroughTenFairValue_df2b321b-e6da-4305-a91e-92dbfbc5b165" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesRollingAfterTenYearsFairValue_dce8a20a-c62f-4033-9ad8-16e37dca6415" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesRollingAfterTenYearsFairValue"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesSingleMaturityDateFairValue_3741f5eb-982c-43cf-a211-ed1ceecc39d1" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesRollingAfterTenYearsFairValue_dce8a20a-c62f-4033-9ad8-16e37dca6415" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_282b8270-40ed-425b-a051-198c812f6ada" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_e37ebace-cd35-403d-a388-30d5accd2f12" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_282b8270-40ed-425b-a051-198c812f6ada" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_e37ebace-cd35-403d-a388-30d5accd2f12" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_e31fcbc8-40f2-4439-a5de-1e2ba872efde" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_282b8270-40ed-425b-a051-198c812f6ada" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_e31fcbc8-40f2-4439-a5de-1e2ba872efde" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_ccdad58a-0181-4479-bd64-648237e14cfc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesNextRollingTwelveMonthsAmortizedCostBasis_37ba668c-8556-4045-905d-846a995797cf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesNextRollingTwelveMonthsAmortizedCostBasis"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_ccdad58a-0181-4479-bd64-648237e14cfc" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesNextRollingTwelveMonthsAmortizedCostBasis_37ba668c-8556-4045-905d-846a995797cf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearTwoThroughFiveAmortizedCostBasis_f22d3a14-bd11-4620-b512-edc7ee3802a1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearTwoThroughFiveAmortizedCostBasis"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_ccdad58a-0181-4479-bd64-648237e14cfc" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearTwoThroughFiveAmortizedCostBasis_f22d3a14-bd11-4620-b512-edc7ee3802a1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearSixThroughTenAmortizedCostBasis_34977912-41c6-449f-b94d-e4b127ea72ae" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearSixThroughTenAmortizedCostBasis"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_ccdad58a-0181-4479-bd64-648237e14cfc" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingYearSixThroughTenAmortizedCostBasis_34977912-41c6-449f-b94d-e4b127ea72ae" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingAfterYearTenAmortizedCostBasis_27b2487a-ab42-4c83-8c31-06718ed9e392" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingAfterYearTenAmortizedCostBasis"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_ccdad58a-0181-4479-bd64-648237e14cfc" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesRollingAfterYearTenAmortizedCostBasis_27b2487a-ab42-4c83-8c31-06718ed9e392" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesFairValue_937c8dc7-3cc3-4192-9a78-194cf4e7ce3f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesFairValue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesSingleMaturityDateFairValue_631c9f35-b583-4c50-8f64-4fd0c834eb4b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesSingleMaturityDateFairValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesFairValue_937c8dc7-3cc3-4192-9a78-194cf4e7ce3f" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesSingleMaturityDateFairValue_631c9f35-b583-4c50-8f64-4fd0c834eb4b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_25c46414-ef87-4efc-ad45-74183b3ca5a2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesFairValue_937c8dc7-3cc3-4192-9a78-194cf4e7ce3f" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_25c46414-ef87-4efc-ad45-74183b3ca5a2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDate_d1e4d555-bb53-4b3b-90fe-6eafdd2007e0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDate"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingWithinOneYear_b7a8df39-6ef8-4d21-b9ee-708b23c8e25a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingWithinOneYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDate_d1e4d555-bb53-4b3b-90fe-6eafdd2007e0" xlink:to="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingWithinOneYear_b7a8df39-6ef8-4d21-b9ee-708b23c8e25a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingAfterOneThroughFiveYears_0b30caab-50ad-4d02-b9a9-070bf8c4a27e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingAfterOneThroughFiveYears"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDate_d1e4d555-bb53-4b3b-90fe-6eafdd2007e0" xlink:to="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingAfterOneThroughFiveYears_0b30caab-50ad-4d02-b9a9-070bf8c4a27e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingAfter5Through10Years_a61c81dd-1ece-45de-ab35-df43288d2c77" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingAfter5Through10Years"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDate_d1e4d555-bb53-4b3b-90fe-6eafdd2007e0" xlink:to="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingAfter5Through10Years_a61c81dd-1ece-45de-ab35-df43288d2c77" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingAfter10Years_b3b08e01-0600-4635-a2f3-6843566bb1f9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingAfter10Years"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDate_d1e4d555-bb53-4b3b-90fe-6eafdd2007e0" xlink:to="loc_us-gaap_DebtSecuritiesHeldToMaturityAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLossMaturityAllocatedAndSingleMaturityDateRollingAfter10Years_b3b08e01-0600-4635-a2f3-6843566bb1f9" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/DebtSecuritiesDebtSecuritiesinanUnrealizedLossPositionDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#DebtSecuritiesDebtSecuritiesinanUnrealizedLossPositionDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/DebtSecuritiesDebtSecuritiesinanUnrealizedLossPositionDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition_e28189e3-b7b9-43cc-a947-485d5c5d81f5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months_448c972f-6da1-4c35-8327-03209a2c4329" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition_e28189e3-b7b9-43cc-a947-485d5c5d81f5" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months_448c972f-6da1-4c35-8327-03209a2c4329" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger_3befbe5e-9676-41e4-ad00-902162a59b86" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition_e28189e3-b7b9-43cc-a947-485d5c5d81f5" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger_3befbe5e-9676-41e4-ad00-902162a59b86" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss_e818966b-2d9a-4acb-ba06-2632d508210e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss_83c6f705-e5a8-4b1c-920a-0f8d696f318d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss_e818966b-2d9a-4acb-ba06-2632d508210e" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss_83c6f705-e5a8-4b1c-920a-0f8d696f318d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss_38867bc2-dc18-49ab-9a99-0cf6119adbf7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss_e818966b-2d9a-4acb-ba06-2632d508210e" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss_38867bc2-dc18-49ab-9a99-0cf6119adbf7" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/LoansReceivableNetCreditQualityIndicatorsforCommercialLoansDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#LoansReceivableNetCreditQualityIndicatorsforCommercialLoansDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/LoansReceivableNetCreditQualityIndicatorsforCommercialLoansDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_b76bdd96-2772-43bd-a9d8-72bc2b5b32d9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestOriginatedMoreThanFiveYearsBeforeCurrentFiscalYear_ab6f2d76-2e73-420b-b994-c750f45a58b0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestOriginatedMoreThanFiveYearsBeforeCurrentFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_b76bdd96-2772-43bd-a9d8-72bc2b5b32d9" xlink:to="loc_us-gaap_FinancingReceivableExcludingAccruedInterestOriginatedMoreThanFiveYearsBeforeCurrentFiscalYear_ab6f2d76-2e73-420b-b994-c750f45a58b0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYear_aac356cf-cf20-4d59-8f63-7c7eedfdb16b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYear"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_b76bdd96-2772-43bd-a9d8-72bc2b5b32d9" xlink:to="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYear_aac356cf-cf20-4d59-8f63-7c7eedfdb16b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear_c0033023-406e-4d56-b45f-ea378c7357e6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_b76bdd96-2772-43bd-a9d8-72bc2b5b32d9" xlink:to="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYear_c0033023-406e-4d56-b45f-ea378c7357e6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestRevolving_cd275f25-c0a0-4959-8ba3-32174335da12" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestRevolving"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_b76bdd96-2772-43bd-a9d8-72bc2b5b32d9" xlink:to="loc_us-gaap_FinancingReceivableExcludingAccruedInterestRevolving_cd275f25-c0a0-4959-8ba3-32174335da12" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear_4391db2a-7082-4d45-9709-78bfc3bb938c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_b76bdd96-2772-43bd-a9d8-72bc2b5b32d9" xlink:to="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYear_4391db2a-7082-4d45-9709-78bfc3bb938c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear_207b82f9-1552-4e82-87d4-568d349d39b6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_b76bdd96-2772-43bd-a9d8-72bc2b5b32d9" xlink:to="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYear_207b82f9-1552-4e82-87d4-568d349d39b6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearFiveOriginatedFourYearsBeforeCurrentFiscalYear_0f825f46-49d1-4cf0-b5c3-3082f4fbc2eb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestYearFiveOriginatedFourYearsBeforeCurrentFiscalYear"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestBeforeAllowanceForCreditLoss_b76bdd96-2772-43bd-a9d8-72bc2b5b32d9" xlink:to="loc_us-gaap_FinancingReceivableExcludingAccruedInterestYearFiveOriginatedFourYearsBeforeCurrentFiscalYear_0f825f46-49d1-4cf0-b5c3-3082f4fbc2eb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoff_9598311d-423c-417b-8b90-4bcf66a582f0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoff"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYearWriteoff_baffd4a8-b568-4ff7-8ee1-5e6324938037" xlink:href="gbci-20230331.xsd#gbci_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYearWriteoff"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoff_9598311d-423c-417b-8b90-4bcf66a582f0" xlink:to="loc_gbci_FinancingReceivableExcludingAccruedInterestYearThreeOriginatedTwoYearsBeforeCurrentFiscalYearWriteoff_baffd4a8-b568-4ff7-8ee1-5e6324938037" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYearWriteoff_154155ef-ead2-4b25-9a84-1e336f02f9ee" xlink:href="gbci-20230331.xsd#gbci_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYearWriteoff"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoff_9598311d-423c-417b-8b90-4bcf66a582f0" xlink:to="loc_gbci_FinancingReceivableExcludingAccruedInterestYearFourOriginatedThreeYearsBeforeCurrentFiscalYearWriteoff_154155ef-ead2-4b25-9a84-1e336f02f9ee" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_FinancingReceivableExcludingAccruedInterestRevolvingWriteoff_18b73625-1fb8-43a0-a5aa-39f743f58807" xlink:href="gbci-20230331.xsd#gbci_FinancingReceivableExcludingAccruedInterestRevolvingWriteoff"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoff_9598311d-423c-417b-8b90-4bcf66a582f0" xlink:to="loc_gbci_FinancingReceivableExcludingAccruedInterestRevolvingWriteoff_18b73625-1fb8-43a0-a5aa-39f743f58807" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYearWriteoff_d9b4f85d-af33-43a2-88ce-dfcbd21c8cbd" xlink:href="gbci-20230331.xsd#gbci_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYearWriteoff"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoff_9598311d-423c-417b-8b90-4bcf66a582f0" xlink:to="loc_gbci_FinancingReceivableExcludingAccruedInterestYearTwoOriginatedFiscalYearBeforeCurrentFiscalYearWriteoff_d9b4f85d-af33-43a2-88ce-dfcbd21c8cbd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_FinancingReceivableExcludingAccruedInterestYearFiveOriginatedFourYearsBeforeCurrentFiscalYearWriteoff_cc1802a5-9097-4f48-aab1-525f21f4a36d" xlink:href="gbci-20230331.xsd#gbci_FinancingReceivableExcludingAccruedInterestYearFiveOriginatedFourYearsBeforeCurrentFiscalYearWriteoff"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoff_9598311d-423c-417b-8b90-4bcf66a582f0" xlink:to="loc_gbci_FinancingReceivableExcludingAccruedInterestYearFiveOriginatedFourYearsBeforeCurrentFiscalYearWriteoff_cc1802a5-9097-4f48-aab1-525f21f4a36d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_FinancingReceivableExcludingAccruedInterestOriginatedMoreThanFiveYearsBeforeCurrentFiscalYearWriteoff_6843dacd-ef88-4696-8f9e-e1cda0c4e05c" xlink:href="gbci-20230331.xsd#gbci_FinancingReceivableExcludingAccruedInterestOriginatedMoreThanFiveYearsBeforeCurrentFiscalYearWriteoff"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoff_9598311d-423c-417b-8b90-4bcf66a582f0" xlink:to="loc_gbci_FinancingReceivableExcludingAccruedInterestOriginatedMoreThanFiveYearsBeforeCurrentFiscalYearWriteoff_6843dacd-ef88-4696-8f9e-e1cda0c4e05c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYearWriteoff_215ccd6a-6e44-4113-816b-9991886f7a0c" xlink:href="gbci-20230331.xsd#gbci_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYearWriteoff"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancingReceivableExcludingAccruedInterestAllowanceForCreditLossWriteoff_9598311d-423c-417b-8b90-4bcf66a582f0" xlink:to="loc_gbci_FinancingReceivableExcludingAccruedInterestYearOneOriginatedCurrentFiscalYearWriteoff_215ccd6a-6e44-4113-816b-9991886f7a0c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/LeasesSummaryDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#LeasesSummaryDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/LeasesSummaryDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAsset_c3802bd9-542e-43a2-a342-d6f732d760e0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseRightOfUseAsset"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAssetBeforeAccumulatedAmortization_ab80bde9-5708-4e08-b932-f67d4fe30a88" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseRightOfUseAssetBeforeAccumulatedAmortization"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseRightOfUseAsset_c3802bd9-542e-43a2-a342-d6f732d760e0" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAssetBeforeAccumulatedAmortization_ab80bde9-5708-4e08-b932-f67d4fe30a88" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAssetAccumulatedAmortization_4a6c5f4d-4e0e-418f-aeb6-0901662c1866" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseRightOfUseAssetAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseRightOfUseAsset_c3802bd9-542e-43a2-a342-d6f732d760e0" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAssetAccumulatedAmortization_4a6c5f4d-4e0e-418f-aeb6-0901662c1866" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/LeasesMaturitiesofLeaseLiabilitiesDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#LeasesMaturitiesofLeaseLiabilitiesDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/LeasesMaturitiesofLeaseLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiability_751bd416-df33-4049-bd60-992394c7408a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiability"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_ec90e7a0-d92a-41ee-8258-bffc72286591" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiability_751bd416-df33-4049-bd60-992394c7408a" xlink:to="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_ec90e7a0-d92a-41ee-8258-bffc72286591" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityCurrent_86ba7704-fd0a-4e4d-935e-6a8e2ff8b794" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiability_751bd416-df33-4049-bd60-992394c7408a" xlink:to="loc_us-gaap_FinanceLeaseLiabilityCurrent_86ba7704-fd0a-4e4d-935e-6a8e2ff8b794" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_409aad93-331e-4ed4-8523-aad061bdb6d8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount_f5d79dba-4d95-40c0-aefe-25c3ee29d86a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_409aad93-331e-4ed4-8523-aad061bdb6d8" xlink:to="loc_us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount_f5d79dba-4d95-40c0-aefe-25c3ee29d86a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiability_03ed170d-2627-43e7-90f0-bb65160cace0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiability"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_409aad93-331e-4ed4-8523-aad061bdb6d8" xlink:to="loc_us-gaap_FinanceLeaseLiability_03ed170d-2627-43e7-90f0-bb65160cace0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_b182901d-c392-4209-8f86-1a9e2f966a7c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_896c24c5-73a5-4e93-93e5-826e648865ee" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeaseLiability_b182901d-c392-4209-8f86-1a9e2f966a7c" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_896c24c5-73a5-4e93-93e5-826e648865ee" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_b2e562a4-bacf-4cd0-becd-468836d25cf2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeaseLiability_b182901d-c392-4209-8f86-1a9e2f966a7c" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_b2e562a4-bacf-4cd0-becd-468836d25cf2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_8a36208d-9e1c-43a3-a136-684a29ff37f1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths_54c1581b-5d50-4d34-9eef-414c5655a900" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_8a36208d-9e1c-43a3-a136-684a29ff37f1" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths_54c1581b-5d50-4d34-9eef-414c5655a900" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo_cf84d2fb-c0dc-469a-a5dd-8f749ec085a8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_8a36208d-9e1c-43a3-a136-684a29ff37f1" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo_cf84d2fb-c0dc-469a-a5dd-8f749ec085a8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree_29705640-0b3f-428b-bf3e-4312259b2af8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_8a36208d-9e1c-43a3-a136-684a29ff37f1" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree_29705640-0b3f-428b-bf3e-4312259b2af8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour_ad5eb35f-f7d7-4496-b4d6-2388caf06f72" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_8a36208d-9e1c-43a3-a136-684a29ff37f1" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour_ad5eb35f-f7d7-4496-b4d6-2388caf06f72" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive_9b46e05a-c546-471f-977e-7a4780191d6b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_8a36208d-9e1c-43a3-a136-684a29ff37f1" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive_9b46e05a-c546-471f-977e-7a4780191d6b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive_4de92ced-e0bd-4848-bbd4-060feb5edeff" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_8a36208d-9e1c-43a3-a136-684a29ff37f1" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive_4de92ced-e0bd-4848-bbd4-060feb5edeff" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/LeasesMaturitiesofLeaseLiabilitiesDetails_1" xlink:type="simple" xlink:href="gbci-20230331.xsd#LeasesMaturitiesofLeaseLiabilitiesDetails_1"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/LeasesMaturitiesofLeaseLiabilitiesDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_08fe511c-a9c3-418e-a32f-cbfbede4233a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths_8438d92a-e137-438a-87e7-15012bb3f583" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_08fe511c-a9c3-418e-a32f-cbfbede4233a" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInNextRollingTwelveMonths_8438d92a-e137-438a-87e7-15012bb3f583" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearTwo_17a086f0-b3bd-45f6-9808-7190f9dbfa7d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearTwo"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_08fe511c-a9c3-418e-a32f-cbfbede4233a" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearTwo_17a086f0-b3bd-45f6-9808-7190f9dbfa7d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearThree_e3b3b44d-bbc3-496c-bfef-6fd639a431d4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearThree"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_08fe511c-a9c3-418e-a32f-cbfbede4233a" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearThree_e3b3b44d-bbc3-496c-bfef-6fd639a431d4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearFour_dc07c647-4628-4536-b3c8-c94c6d6d5eaf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearFour"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_08fe511c-a9c3-418e-a32f-cbfbede4233a" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearFour_dc07c647-4628-4536-b3c8-c94c6d6d5eaf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearFive_7d8dd087-e93e-4d6a-8dfc-40759745e718" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearFive"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_08fe511c-a9c3-418e-a32f-cbfbede4233a" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingYearFive_7d8dd087-e93e-4d6a-8dfc-40759745e718" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingAfterYearFive_1323a7ee-e8d8-4b65-bfd4-dcfd5a37a0d3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingAfterYearFive"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_08fe511c-a9c3-418e-a32f-cbfbede4233a" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueInRollingAfterYearFive_1323a7ee-e8d8-4b65-bfd4-dcfd5a37a0d3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_253624e5-494a-495b-8675-92df397a13d1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_8f057853-69b7-4900-8e0a-e3ae93f4e0c6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_253624e5-494a-495b-8675-92df397a13d1" xlink:to="loc_us-gaap_OperatingLeaseLiability_8f057853-69b7-4900-8e0a-e3ae93f4e0c6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_9ad96cbd-1055-4e9a-b4aa-60fe11d0b4a8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_253624e5-494a-495b-8675-92df397a13d1" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_9ad96cbd-1055-4e9a-b4aa-60fe11d0b4a8" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/LeasesComponentsofLeaseExpenseDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#LeasesComponentsofLeaseExpenseDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/LeasesComponentsofLeaseExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCost_2e348993-2c11-4ccc-9ece-bcc7058cadcc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeaseCost"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_72343ea3-a24a-4d78-8687-72510a0e21b3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseRightOfUseAssetAmortization"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LeaseCost_2e348993-2c11-4ccc-9ece-bcc7058cadcc" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_72343ea3-a24a-4d78-8687-72510a0e21b3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseInterestExpense_9b5cf5d7-6003-4762-8542-34c75290bea2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseInterestExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LeaseCost_2e348993-2c11-4ccc-9ece-bcc7058cadcc" xlink:to="loc_us-gaap_FinanceLeaseInterestExpense_9b5cf5d7-6003-4762-8542-34c75290bea2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseCost_d88ad00f-9ff4-47f5-9eed-1bdda97b26c3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseCost"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LeaseCost_2e348993-2c11-4ccc-9ece-bcc7058cadcc" xlink:to="loc_us-gaap_OperatingLeaseCost_d88ad00f-9ff4-47f5-9eed-1bdda97b26c3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermLeaseCost_c84b5fbc-faf8-43f9-a4a0-12a6fff4d29a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShortTermLeaseCost"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LeaseCost_2e348993-2c11-4ccc-9ece-bcc7058cadcc" xlink:to="loc_us-gaap_ShortTermLeaseCost_c84b5fbc-faf8-43f9-a4a0-12a6fff4d29a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableLeaseCost_dbb0182c-b2e8-4044-9852-afde50a6bde9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableLeaseCost"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LeaseCost_2e348993-2c11-4ccc-9ece-bcc7058cadcc" xlink:to="loc_us-gaap_VariableLeaseCost_dbb0182c-b2e8-4044-9852-afde50a6bde9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubleaseIncome_c654095b-b9c2-4ad4-a139-77d2bf6c8681" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubleaseIncome"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LeaseCost_2e348993-2c11-4ccc-9ece-bcc7058cadcc" xlink:to="loc_us-gaap_SubleaseIncome_c654095b-b9c2-4ad4-a139-77d2bf6c8681" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/VariableInterestEntitiesFutureUnfundedContingentCommitmentsDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#VariableInterestEntitiesFutureUnfundedContingentCommitmentsDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/VariableInterestEntitiesFutureUnfundedContingentCommitmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_QualifiedAffordableHousingProjectInvestmentsCommitment_ffd8016a-6187-4160-b3dc-1fadca0fc206" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_QualifiedAffordableHousingProjectInvestmentsCommitment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentsFutureMinimumPaymentsRemainderOfFiscalYear_53a000b3-1aa4-4e00-a1ec-1850c4d4c2a0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherCommitmentsFutureMinimumPaymentsRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_QualifiedAffordableHousingProjectInvestmentsCommitment_ffd8016a-6187-4160-b3dc-1fadca0fc206" xlink:to="loc_us-gaap_OtherCommitmentsFutureMinimumPaymentsRemainderOfFiscalYear_53a000b3-1aa4-4e00-a1ec-1850c4d4c2a0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentDueInNextTwelveMonths_c52ac4a7-121b-4f07-a5e1-885d769e334b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherCommitmentDueInNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_QualifiedAffordableHousingProjectInvestmentsCommitment_ffd8016a-6187-4160-b3dc-1fadca0fc206" xlink:to="loc_us-gaap_OtherCommitmentDueInNextTwelveMonths_c52ac4a7-121b-4f07-a5e1-885d769e334b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentDueInSecondYear_34cfffe4-a8a4-487b-9e9c-db274b6710f5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherCommitmentDueInSecondYear"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_QualifiedAffordableHousingProjectInvestmentsCommitment_ffd8016a-6187-4160-b3dc-1fadca0fc206" xlink:to="loc_us-gaap_OtherCommitmentDueInSecondYear_34cfffe4-a8a4-487b-9e9c-db274b6710f5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentDueInThirdYear_3622ada0-0664-4a3e-a58c-418d6f6ec3b0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherCommitmentDueInThirdYear"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_QualifiedAffordableHousingProjectInvestmentsCommitment_ffd8016a-6187-4160-b3dc-1fadca0fc206" xlink:to="loc_us-gaap_OtherCommitmentDueInThirdYear_3622ada0-0664-4a3e-a58c-418d6f6ec3b0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentDueInFourthYear_b0327a58-695f-41e1-ad82-71e6f30e35c7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherCommitmentDueInFourthYear"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_QualifiedAffordableHousingProjectInvestmentsCommitment_ffd8016a-6187-4160-b3dc-1fadca0fc206" xlink:to="loc_us-gaap_OtherCommitmentDueInFourthYear_b0327a58-695f-41e1-ad82-71e6f30e35c7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_OtherCommitmentToBePaidAfterYearFour_f3b5aa52-5eff-4554-a529-ebaee6e7cbba" xlink:href="gbci-20230331.xsd#gbci_OtherCommitmentToBePaidAfterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_QualifiedAffordableHousingProjectInvestmentsCommitment_ffd8016a-6187-4160-b3dc-1fadca0fc206" xlink:to="loc_gbci_OtherCommitmentToBePaidAfterYearFour_f3b5aa52-5eff-4554-a529-ebaee6e7cbba" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/OtherExpensesDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#OtherExpensesDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/OtherExpensesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherNoninterestExpense"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_ConsultingFees_082b3097-023f-49c4-93d3-4120c2012502" xlink:href="gbci-20230331.xsd#gbci_ConsultingFees"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_gbci_ConsultingFees_082b3097-023f-49c4-93d3-4120c2012502" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_LoanRelatedExpenses_6f3a55f6-65b3-4fde-96c7-18b0da7eb58b" xlink:href="gbci-20230331.xsd#gbci_LoanRelatedExpenses"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_gbci_LoanRelatedExpenses_6f3a55f6-65b3-4fde-96c7-18b0da7eb58b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_TelephoneExpenses_91e4ede5-1beb-4fbc-869e-9d9576bed9ab" xlink:href="gbci-20230331.xsd#gbci_TelephoneExpenses"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_gbci_TelephoneExpenses_91e4ede5-1beb-4fbc-869e-9d9576bed9ab" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_VIEWriteDownsLossesAndOtherExpenses_0a4fb3c7-bfce-468e-b025-afa554efa60e" xlink:href="gbci-20230331.xsd#gbci_VIEWriteDownsLossesAndOtherExpenses"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_gbci_VIEWriteDownsLossesAndOtherExpenses_0a4fb3c7-bfce-468e-b025-afa554efa60e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_DebitCardExpense_7121d908-c2a6-40de-ad0f-eca21d052fe1" xlink:href="gbci-20230331.xsd#gbci_DebitCardExpense"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_gbci_DebitCardExpense_7121d908-c2a6-40de-ad0f-eca21d052fe1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessDevelopment_81201d9c-20b6-4c9d-ae34-fde444f4e8b0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessDevelopment"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_us-gaap_BusinessDevelopment_81201d9c-20b6-4c9d-ae34-fde444f4e8b0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PostageExpense_796fd13d-ce78-40d1-af02-746d2227a4e7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PostageExpense"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_us-gaap_PostageExpense_796fd13d-ce78-40d1-af02-746d2227a4e7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SuppliesExpense_45a081b4-a2ad-46b6-9d0d-6e849b1dd504" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SuppliesExpense"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_us-gaap_SuppliesExpense_45a081b4-a2ad-46b6-9d0d-6e849b1dd504" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_MiscellaneousEmployeeExpenses_4cab2400-989e-4438-b4b1-09b25e514b64" xlink:href="gbci-20230331.xsd#gbci_MiscellaneousEmployeeExpenses"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_gbci_MiscellaneousEmployeeExpenses_4cab2400-989e-4438-b4b1-09b25e514b64" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationIntegrationRelatedCosts_679d75bc-aa5d-46d6-ab32-d6cf750ee6d4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationIntegrationRelatedCosts"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_us-gaap_BusinessCombinationIntegrationRelatedCosts_679d75bc-aa5d-46d6-ab32-d6cf750ee6d4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LegalFees_4d805a75-1768-4ac6-af8b-4269bc50b514" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LegalFees"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_us-gaap_LegalFees_4d805a75-1768-4ac6-af8b-4269bc50b514" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_DepositRelatedExpenses_7bececbd-52e1-4b88-8707-8572dd5c8466" xlink:href="gbci-20230331.xsd#gbci_DepositRelatedExpenses"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_gbci_DepositRelatedExpenses_7bececbd-52e1-4b88-8707-8572dd5c8466" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_AccountingFees_9653c4c7-710e-47c1-81c9-4936dca85a59" xlink:href="gbci-20230331.xsd#gbci_AccountingFees"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_gbci_AccountingFees_9653c4c7-710e-47c1-81c9-4936dca85a59" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnDispositionOfAssets1_b5da33d7-d7c3-4327-bbe2-547ef400f3ff" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainLossOnDispositionOfAssets1"/>
    <link:calculationArc order="14" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_us-gaap_GainLossOnDispositionOfAssets1_b5da33d7-d7c3-4327-bbe2-547ef400f3ff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCostAndExpenseOperating_a9da49b9-85e2-4578-a03f-b03b87bcec8b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherCostAndExpenseOperating"/>
    <link:calculationArc order="15" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherNoninterestExpense_116fab6a-53d8-4c41-aec4-9b3a23576f66" xlink:to="loc_us-gaap_OtherCostAndExpenseOperating_a9da49b9-85e2-4578-a03f-b03b87bcec8b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/AccumulatedOtherComprehensiveLossIncomeDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#AccumulatedOtherComprehensiveLossIncomeDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/AccumulatedOtherComprehensiveLossIncomeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_a6d0f67b-f57c-4292-ba3c-e0b17a7ff861" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_211c1733-4deb-448c-b199-60f64a791591" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_a6d0f67b-f57c-4292-ba3c-e0b17a7ff861" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_211c1733-4deb-448c-b199-60f64a791591" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_95c86ac1-62c0-49d3-9623-88c6291954b0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_a6d0f67b-f57c-4292-ba3c-e0b17a7ff861" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_95c86ac1-62c0-49d3-9623-88c6291954b0" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/EarningsPerShareDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#EarningsPerShareDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/EarningsPerShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_6550bafc-4684-4a6e-b6f5-23b82673453d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_64fc70cc-ec15-4aed-bb72-25524ba96dd0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_6550bafc-4684-4a6e-b6f5-23b82673453d" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_64fc70cc-ec15-4aed-bb72-25524ba96dd0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_092ba668-8673-4b23-ac90-7859b836c79f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_6550bafc-4684-4a6e-b6f5-23b82673453d" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_092ba668-8673-4b23-ac90-7859b836c79f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/FairValueofAssetsandLiabilitiesFairValueMeasurementsonaRecurringBasisDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#FairValueofAssetsandLiabilitiesFairValueMeasurementsonaRecurringBasisDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/FairValueofAssetsandLiabilitiesFairValueMeasurementsonaRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_dac652e0-2364-41b5-82ef-d7fd598da8ba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_9c50ace6-50ac-4fd3-91d0-9287c62b385a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_dac652e0-2364-41b5-82ef-d7fd598da8ba" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_9c50ace6-50ac-4fd3-91d0-9287c62b385a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansHeldForSaleFairValueDisclosure_21ca3e83-d50f-493b-ba5b-26055a494b78" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LoansHeldForSaleFairValueDisclosure"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_dac652e0-2364-41b5-82ef-d7fd598da8ba" xlink:to="loc_us-gaap_LoansHeldForSaleFairValueDisclosure_21ca3e83-d50f-493b-ba5b-26055a494b78" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssets_db78856b-2210-413d-9e0f-5ce0015403a6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_dac652e0-2364-41b5-82ef-d7fd598da8ba" xlink:to="loc_us-gaap_DerivativeAssets_db78856b-2210-413d-9e0f-5ce0015403a6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure_9e14efbc-c7e1-4f69-9a59-98348b69ae75" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancialLiabilitiesFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilities_971ab567-868e-4fdf-a561-181b05542e8a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DerivativeLiabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure_9e14efbc-c7e1-4f69-9a59-98348b69ae75" xlink:to="loc_us-gaap_DerivativeLiabilities_971ab567-868e-4fdf-a561-181b05542e8a" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/FairValueofAssetsandLiabilitiesFairValueMeasurementsonaNonRecurringBasisDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#FairValueofAssetsandLiabilitiesFairValueMeasurementsonaNonRecurringBasisDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/FairValueofAssetsandLiabilitiesFairValueMeasurementsonaNonRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_b00e8fae-79ea-4191-838a-1917cd62b186" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_CollateralDependentImpairedLoansOwnedFairValueDisclosure_d54d8306-6dc8-444a-846e-97bc45a6ff4f" xlink:href="gbci-20230331.xsd#gbci_CollateralDependentImpairedLoansOwnedFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_b00e8fae-79ea-4191-838a-1917cd62b186" xlink:to="loc_gbci_CollateralDependentImpairedLoansOwnedFairValueDisclosure_d54d8306-6dc8-444a-846e-97bc45a6ff4f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.glacierbancorp.com/role/FairValueofAssetsandLiabilitiesCarryingAmountandEstimatedFairValueofFinancialInstrumentsNotCarriedatFairValueDetails" xlink:type="simple" xlink:href="gbci-20230331.xsd#FairValueofAssetsandLiabilitiesCarryingAmountandEstimatedFairValueofFinancialInstrumentsNotCarriedatFairValueDetails"/>
  <link:calculationLink xlink:role="http://www.glacierbancorp.com/role/FairValueofAssetsandLiabilitiesCarryingAmountandEstimatedFairValueofFinancialInstrumentsNotCarriedatFairValueDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_gbci_FinancialAssetsFairValueDisclosure_146b5f2b-adb4-4c2e-8734-6e3d371f7740" xlink:href="gbci-20230331.xsd#gbci_FinancialAssetsFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_ffd68baa-2d16-4848-af91-d6b4730613d8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_FinancialAssetsFairValueDisclosure_146b5f2b-adb4-4c2e-8734-6e3d371f7740" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_ffd68baa-2d16-4848-af91-d6b4730613d8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_HeldToMaturityInvestmentsFairValueDisclosure_a8658cee-4c6f-4d45-9204-7b57b1f5eb5b" xlink:href="gbci-20230331.xsd#gbci_HeldToMaturityInvestmentsFairValueDisclosure"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_FinancialAssetsFairValueDisclosure_146b5f2b-adb4-4c2e-8734-6e3d371f7740" xlink:to="loc_gbci_HeldToMaturityInvestmentsFairValueDisclosure_a8658cee-4c6f-4d45-9204-7b57b1f5eb5b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansReceivableFairValueDisclosure_591f965e-37d8-4b35-a8ae-8f476dd4686a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LoansReceivableFairValueDisclosure"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_gbci_FinancialAssetsFairValueDisclosure_146b5f2b-adb4-4c2e-8734-6e3d371f7740" xlink:to="loc_us-gaap_LoansReceivableFairValueDisclosure_591f965e-37d8-4b35-a8ae-8f476dd4686a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure_1480575e-91c5-4ed2-b444-28c2821163a1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancialLiabilitiesFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsFairValueDisclosure_8e52b64a-9e88-4d3b-8369-c5366dce0e20" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DepositsFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure_1480575e-91c5-4ed2-b444-28c2821163a1" xlink:to="loc_us-gaap_DepositsFairValueDisclosure_8e52b64a-9e88-4d3b-8369-c5366dce0e20" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FederalFundsPurchasedAndSecuritiesLoanedOrSoldUnderAgreementsToRepurchaseFairValueDisclosure_62b04330-eacf-4f0a-b591-9492256f0df1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FederalFundsPurchasedAndSecuritiesLoanedOrSoldUnderAgreementsToRepurchaseFairValueDisclosure"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure_1480575e-91c5-4ed2-b444-28c2821163a1" xlink:to="loc_us-gaap_FederalFundsPurchasedAndSecuritiesLoanedOrSoldUnderAgreementsToRepurchaseFairValueDisclosure_62b04330-eacf-4f0a-b591-9492256f0df1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisSubordinatedDebtObligations_41f2bad7-9736-4bf6-a524-ebeab4db762f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisSubordinatedDebtObligations"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure_1480575e-91c5-4ed2-b444-28c2821163a1" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisSubordinatedDebtObligations_41f2bad7-9736-4bf6-a524-ebeab4db762f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FederalHomeLoanBankBorrowingsFairValueDisclosure_cc18b1b5-67a5-4c67-97a5-714916294612" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FederalHomeLoanBankBorrowingsFairValueDisclosure"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure_1480575e-91c5-4ed2-b444-28c2821163a1" xlink:to="loc_us-gaap_FederalHomeLoanBankBorrowingsFairValueDisclosure_cc18b1b5-67a5-4c67-97a5-714916294612" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_gbci_FederalReserveBankBorrowingsFairValueDisclosure_1fede458-c2f4-4483-8f35-7f96695c2317" xlink:href="gbci-20230331.xsd#gbci_FederalReserveBankBorrowingsFairValueDisclosure"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosure_1480575e-91c5-4ed2-b444-28c2821163a1" xlink:to="loc_gbci_FederalReserveBankBorrowingsFairValueDisclosure_1fede458-c2f4-4483-8f35-7f96695c2317" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
